Cart
sales@molnova.com
SARS-CoV-2 nsp13-IN-1
CAS No. 1005304-44-8
SARS-CoV-2 nsp13-IN-1( —— )
Catalog No. M35639 CAS No. 1005304-44-8
SARS-CoV-2 nsp13-IN-1 (compound C1) is a potent inhibitor of nsp13 (non-structural protein 13), selectively inhibiting nsp13 ssDNA+ATPase with an IC50 of 6 μM, but not ssDNA-ATPase, and can be used to study COVID-19.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 59 | Get Quote |
|
| 5MG | 85 | Get Quote |
|
| 10MG | 140 | Get Quote |
|
| 25MG | 227 | Get Quote |
|
| 50MG | 336 | Get Quote |
|
| 100MG | 488 | Get Quote |
|
| 500MG | 1062 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameSARS-CoV-2 nsp13-IN-1
-
NoteResearch use only, not for human use.
-
Brief DescriptionSARS-CoV-2 nsp13-IN-1 (compound C1) is a potent inhibitor of nsp13 (non-structural protein 13), selectively inhibiting nsp13 ssDNA+ATPase with an IC50 of 6 μM, but not ssDNA-ATPase, and can be used to study COVID-19.
-
DescriptionSARS-CoV-2 nsp13-IN-1 (compound C1) is a potent nsp13 (non-structural protein 13) inhibitor. SARS-CoV-2 nsp13-IN-1 only inhibits nsp13 ssDNA+ ATPase, with an IC50 of 6 μM. SARS-CoV-2 nsp13-IN-1 does not inhibit ssDNA- ATPase. SARS-CoV-2 nsp13-IN-1 can be used for COVID-19 research.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayImmunology/Inflammation
-
TargetAntiviral
-
RecptorAntiviral
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1005304-44-8
-
Formula Weight432.47
-
Molecular FormulaC27H20N4O2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 41.67 mg/mL (96.35 mM; Ultrasonic (<60°C)
-
SMILESCC1=NC2=C(C=CC=N2)C(=O)N1C1=CC=C(NC(=O)C2=CC=C(C=C2)C2=CC=CC=C2)C=C1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Yazdi AK, et al. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors. ACS Infect Dis. 2022 Jul 13.?
molnova catalog
related products
-
SIRT1-IN-1
SIRT1-IN-1 is a selective inhibitor of SIRT1 with an IC50 of 205 nM. SIRT1-IN-1 is an inhibitor of cytomegalovirus (CMV) with antiviral activity.
-
GPS491
GPS491 has antiviral activity and inhibits HIV-1, adenovirus, and coronavirus replication by altering RNA processing.
-
LCC-12 FA
LCC-12 FA is a dimer composed of metformin that induces a decrease in the NAD(H) pool by targeting mitochondrial copper(ii).
